$89.95

Useful Statistical Approaches for Addressing Multiplicity Issues Includes practical examples from recent trials Bringing together leading statisticians, scientists, and clinicians from the pharmaceutical industry, academia, and regulatory agencies, Multiple Testing Problems in Pharmaceutical Statistics explores the rapidly growing area of multiple comparison research with an emphasis on pharmaceutical applications. In each chapter, the expert contributors describe important multiplicity problems encountered in pre-clinical and clinical trial settings. The book begins with a broad introduction from a regulatory perspective to different types of multiplicity problems that commonly arise in confirmatory controlled clinical trials, before giving an overview of the concepts, principles, and procedures of multiple testing. It then presents statistical methods for analyzing clinical dose response studies that compare several dose levels with a control as well as statistical methods for analyzing multiple endpoints in clinical trials. After covering gatekeeping procedures for testing hierarchically ordered hypotheses, the book discusses statistical approaches for the design and analysis of adaptive designs and related confirmatory hypothesis testing problems. The final chapter focuses on the design of pharmacogenomic studies based on established statistical principles. It also describes the analysis of data collected in these studies, taking into account the numerous multiplicity issues that occur. This volume explains how to solve critical issues in multiple testing encountered in pre-clinical and clinical trial applications. It presents the necessary statistical methodology, along with examples and software code to show how to use the methods in practice.

$9.99

The fun and easy way to get down to business with statistics Stymied by statistics? No fear ? this friendly guide offers clear, practical explanations of statistical ideas, techniques, formulas, and calculations, with lots of examples that show you how these concepts apply to your everyday life. Statistics For Dummies shows you how to interpret and critique graphs and charts, determine the odds with probability, guesstimate with confidence using confidence intervals, set up and carry out a hypothesis test, compute statistical formulas, and more. Tracks to a typical first semester statistics course Updated examples resonate with today's students Explanations mirror teaching methods and classroom protocol Packed with practical advice and real-world problems, Statistics For Dummies gives you everything you need to analyze and interpret data for improved classroom or on-the-job performance.

$16.99

A brain explains... Most math and science study guides are dry and difficult but this is the exception. Following the successful The Humongous Books in calculus and algebra bestselling author Mike Kelley takes a typical statistics workbook full of solved problems and writes notes in the margins adding missing steps and simplifying concepts and solutions. By learning how to interpret and solve problems as they are presented in statistics courses students prepare to solve those difficult problems that were never discussed in class but are always on exams. *With annotated notes and explanations of missing steps throughout like no other statistics workbook on the market * An award-winning former math teacher whose website (calculus-help. com) reaches thousands every month providing exposure for all his booksA brain explains... Most math and science study guides are dry and difficult but this is the exception. Following the successful The Humongous Books in calculus and algebra bestselling author Mike Kelley takes a typical statistics workbook full of solved problems and writes notes in the margins adding missing steps and simplifying concepts and solutions. By learning how to interpret and solve problems as they are presented in statistics courses students prepare to solve those difficult problems that were never discussed in class but are always on exams. *With annotated notes and explanations of missing steps throughout like no other statistics workbook on the market * An award-winning former math teacher whose website (calculus-help. com) reaches thousands every month providing exposure for all his books

$45

Probability and Statistics, Revised Edition deals with the history of probability, describing the modern concept of randomness and examining "pre-probabilistic" ideas of what most people today would characterize as randomness. This revised book documents some historically important early uses of probability to illustrate some very important probabilistic questions. It goes on to explore statistics and the generations of mathematicians and non-mathematicians who began to address problems in statistical analysis, including the statistical structure of data sets as well as the theory of sampling and the characterization of the nature of variation. The final chapter describes the role of statistics in the development, testing, licensure, and subsequent study of vaccines. A new chapter has been added that gives special attention to vaccines for measles, polio, pertussis, and rubella.

$205

Statisticians and philosophers of science have many common interests but restricted communication with each other. This volume aims to remedy these shortcomings. It provides state-of-the-art research in the area of Philosophy of Statistics by encouraging numerous experts to communicate with one another without feeling restricted by their disciplines or thinking piecemeal in their treatment of issues. A second goal of this book is to present work in the field without bias toward any particular statistical paradigm. Broadly speaking, the essays in this Handbook are concerned with problems of induction, statistics and probability. For centuries, foundational problems like induction have been among philosophers' favorite topics; recently, however, non-philosophers have increasingly taken a keen interest in these issues. This volume accordingly contains papers by both philosophers and non-philosophers, including scholars from nine academic disciplines. Provides a bridge between philosophy and current scientific findings Covers theory and applications Encourages multi-disciplinary dialogue

$110

New Edition of a Classic Guide to Statistical Applications in the Biomedical Sciences In the last decade, there have been significant changes in the way statistics is incorporated into biostatistical, medical, and public health research. Addressing the need for a modernized treatment of these statistical applications, Basic Statistics, Fourth Edition presents relevant, up-to-date coverage of research methodology using careful explanations of basic statistics and how they are used to address practical problems that arise in the medical and public health settings. Through concise and easy-to-follow presentations, readers will learn to interpret and examine data by applying common statistical tools, such as sampling, random assignment, and survival analysis. Continuing the tradition of its predecessor, this new edition outlines a thorough discussion of different kinds of studies and guides readers through the important, related decision-making processes such as determining what information is needed and planning the collections process. The book equips readers with the knowledge to carry out these practices by explaining the various types of studies that are commonly conducted in the fields of medical and public health, and how the level of evidence varies depending on the area of research. Data screening and data entry into statistical programs is explained and accompanied by illustrations of statistical analyses and graphs. Additional features of the Fourth Edition include: A new chapter on data collection that outlines the initial steps in planning biomedical and public health studies A new chapter on nonparametric statistics that includes a discussion and application of the Sign test, the Wilcoxon Signed Rank test, and the Wilcoxon Rank Sum test and its relationship to the Mann-Whitney U test An updated introduction to survival analysis that includes the Kaplan Meier method for graphing the survival function and a brief introduction to tests for comparing survival functions Incorporation of modern statistical software, such as SAS, Stata, SPSS, and Minitab into the presented discussion of data analysis Updated references at the end of each chapter Basic Statistics , Fourth Edition is an ideal book for courses on biostatistics, medicine, and public health at the upper-undergraduate and graduate levels. It is also appropriate as a reference for researchers and practitioners who would like to refresh their fundamental understanding of statistical techniques.